К вопросу лечения и заполнения костных дефектов инфекционной этиологии. Обзор литературы
DOI:
https://doi.org/10.52889/1684-9280-2025-76-1-4-14Ключевые слова:
хронический остеомиелит, Staphylococcus aureus, биопленки, лечение, заменители кости, наноцеллюлоза, костный аллографтАннотация
Вопрос лечения и заполнения костных дефектов является актуальным по сей день. Остеомиелит - инфекционное воспаление всех элементов кости, затрагивающее костный мозг, губчатое и компактное вещество, надкостницу. Диагностика и лечение хронического остеомиелита является актуальной задачей травматологии и ортопедии. Данный постулат обусловлен высоким процентом осложнений, большими экономическими затратами при лечении пациентов, длительностью терапии.
Поиск и обзор литературы проведен в феврале 2024 года и осуществлялся по ключевым словам на сайтах Web of science, Scopus, PubMed, Wiley. Из полученной выборки отбирались статьи, соответствующие тематике исследования, предпочтение отдавалось работам 2014-2024 гг. Также изучены и включены в обзор диссертации травматолого-ортопедического профиля, выполненные на кафедре хирургических болезней Медицинского университета Караганды.
Условно обзор состоит из нескольких частей: 1) экспликация структурно-функциональных свойств биопленок на примере Staphylococcus aureus, как наиболее частого инфекционного этиофактора хронического остеомиелита; 2) сравнительно описательный анализ современных заполнителей костных дефектов; 3) дескрипция научных достижений кафедры хирургических болезней Медицинского университета Караганды в области применения костного аллографта. Такая дифференциация, по мнению авторов, позволила наиболее полно раскрыть тему статьи.
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